Tesamorelin (5mg Vial) Dosage Protocol

Quickstart Highlights

Tesamorelin 5mg dosage protocol is designed to stimulate growth hormone release and support body composition improvements through subcutaneous injections administered five days per week.

  • Typical daily dosage range: 1 mg to 2 mg, Monday–Friday
  • Subcutaneous injections, preferably in the morning (fasted state)
  • Reconstitute with 1 mL for practical measurement (5 mg/mL concentration)
  • Store lyophilized vials in the freezer; reconstituted solution in the refrigerator
  • Allow for 2 consecutive off-days each week to maintain receptor sensitivity
Tesamorelin Vial

Dosing & Reconstitution Guide

Educational guide for reconstitution and dosing protocol

Standard / Gradual Approach (1 mL = 5 mg/mL)

Weeks Daily Dosage (mg) Units (per injection)
1–4 1 mg (Mon–Fri) 20 units
5–8 1 mg (Mon–Fri) 20 units

A moderate protocol of 1 mg daily (5 days/week), using 1 mL of bacteriostatic water to achieve a 5 mg/mL concentration. Each 1 mg dose corresponds to 0.2 mL (20 units) on a 100-unit insulin syringe.

  1. Draw 1.0 mL of bacteriostatic water into a sterile syringe.
  2. Inject slowly along the vial wall to reduce foaming.
  3. Gently swirl until the powder dissolves—avoid vigorous shaking.
  4. Label the vial with the date and store at 2–8°C (refrigerator).
  5. Use within 30 days; avoid repeated freeze-thaw cycles.

Advanced / Aggressive Approach (1 mL = 5 mg/mL)

Weeks Daily Dosage (mg) Units (per injection)
1–4 2 mg (Mon–Fri) 40 units
5–8 2 mg (Mon–Fri) 40 units

A more intensive protocol at 2 mg daily (5 days/week). With 1 mL of reconstitution, each 2 mg dose equals 0.4 mL (40 units). Note that each vial contains 5 mg total; advanced users may need multiple vials per week.

  1. Draw 1.0 mL of bacteriostatic water into a sterile syringe.
  2. Slowly inject along the vial wall to minimize foam.
  3. Gently roll/swirl; avoid shaking vigorously.
  4. Refrigerate at 2–8°C; use within 30 days.
  5. Do not freeze after reconstitution; prevent repeated freeze-thaw cycles.

Note: This guide is for educational purposes only. Always consult a qualified professional for personalized advice.

Protocol Overview

A concise summary of this daily (Monday–Friday) regimen.

  • Goal: Boost endogenous growth hormone release and improve body composition
  • Schedule: Daily subcutaneous injections (5x/week) for 8–16 weeks
  • Dose Range: 1 mg to 2 mg per day (5 mg to 10 mg total weekly)
  • Reconstitution: Use 1 mL for user-friendly measurements (5 mg/mL)
  • Storage: Keep lyophilized vials frozen; refrigerate after mixing

Dosing Protocol

Suggested daily injection approach for optimal GH stimulation.

  • Daily Dose: 1 mg (standard) or 2 mg (advanced), Monday–Friday
  • Frequency: Subcutaneous injection once per day
  • Cycle Length: 8–16 weeks (longer if desired)
  • Washout Period: Weekends off (2 days) to maintain receptor sensitivity
  • Timing: Preferably in the morning (fasted state)

Storage Instructions

Proper storage ensures peptide integrity.

  • Lyophilized: Freeze until mixing (−20°C or below)
  • Reconstituted: Refrigerate at 2–8°C
  • Use within 30 days of reconstitution
  • Avoid repeated freeze-thaw cycles

Supplies Needed

Ensure you have these on hand for an 8–16 week protocol.

  • Peptide Vials (5 mg each):
    • Standard (1 mg/day, 5 days/wk = 5 mg/wk): ~1 vial per week
    • Advanced (2 mg/day, 5 days/wk = 10 mg/wk): ~2 vials per week
    Adjust total vials for desired cycle length (e.g., 8, 12, or 16 weeks).
  • Insulin Syringes: One syringe per injection day
    • 8 wks ≈ 40 syringes (standard or advanced)
  • Bacteriostatic Water: 1× 30 mL (sufficient for multiple vials)
  • Alcohol Swabs: 1 box for cleaning stoppers & injection sites

Important Notes

Practical tips to enhance safety and efficacy.

  • Always use sterile insulin syringes; rotate injection sites to avoid tissue damage.
  • Administer in the morning (fasted) for optimal GH response.
  • Allow for 2 consecutive off-days per week to maintain receptor sensitivity.
  • Monitor for any adverse reactions; consult a professional if concerns arise.

How This Works

Tesamorelin is a growth hormone-releasing hormone (GHRH) analog that prompts the pituitary to release growth hormone.

  • GH Release: Increases pituitary output of growth hormone
  • Metabolic Impact: Potentially aids in reducing visceral fat and improving body composition
  • Additional Research: Explored for muscle support and fat loss beyond HIV-related lipodystrophy

Potential Benefits & Side Effects

Most users observe improved GH profiles, though individual responses vary.

  • May help decrease abdominal fat in HIV-associated lipodystrophy
  • Could support lean mass and overall metabolic function
  • Common mild sides: injection site irritation, swelling, or redness
  • Rarely, joint discomfort, nausea, or headaches can occur

Lifestyle Factors

Complementary strategies for maximizing results.

  • Combine with a balanced, protein-rich diet and regular exercise
  • Prioritize sleep and stress management to optimize hormonal balance
  • Stay hydrated and follow consistent injection times for best outcomes

Injection Technique

Simple guidelines for safe daily injections.

  • Clean vial rubber stopper & injection site with alcohol swabs
  • Insert needle at a 45–90° angle into subcutaneous tissue
  • Inject slowly & rotate sites (abdomen, thigh, etc.)

Important Note

This guide is for educational purposes only. Always consult a qualified healthcare provider before starting or modifying any therapy.

 

References

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