Ara-290 (16 mg Vial) Dosage Protocol
Quickstart Highlights
Ara-290 16 mg dosage protocol is grounded in peer-reviewed trials for neuropathic pain and tissue repair using daily subcutaneous injections.
- Clinically effective range: 2 – 4 mg per day
- Standard cycle: 28 days on, then 28 days off
- Reconstitute to 8 mg / mL (2 mL) for easy 25–50 unit draws
- Advanced users may concentrate to 10 mg / mL (1.6 mL) for higher doses
- Store lyophilized frozen; refrigerate after reconstitution
Dosing & Reconstitution Guide
Educational guide for reconstitution and dosing protocol
Standard / Gradual Approach (2 mL = 8 mg/mL)
| Week | Daily Dose (mg) | Units (0.01 mL) |
|---|---|---|
| 1 – 2 | 2 mg (2 000 µg) | 25 u (0.25 mL) |
| 3 – 4 | 4 mg (4 000 µg) | 50 u (0.50 mL) |
Ideal for first-time users or maintenance. Reconstitute with 2.0 mL bacteriostatic water to yield 8 mg/mL. All injections remain 25–50 units, comfortably above the 10-unit accuracy threshold.
- Draw 2.0 mL bacteriostatic water into a sterile syringe.
- Inject slowly down the vial wall; swirl gently until clear.
- Label: “16 mg / 2 mL = 8 mg/mL (1 u = 80 µg)”.
- Refrigerate (2 – 8 °C).
Advanced / Aggressive Approach (1.6 mL = 10 mg/mL)
| Week | Daily Dose (mg) | Units (0.01 mL) |
|---|---|---|
| 1 – 4 | 4 mg (4 000 µg) | 40 u (0.40 mL) |
| Optional High-Dose* | 8 mg (8 000 µg) | 80 u (0.80 mL) |
Suited for severe neuropathic pain or intensive tissue-repair studies under professional oversight. Reconstitute with 1.6 mL bacteriostatic water to create 10 mg/mL. *80 units exceeds 60 u; use a full 1 mL syringe or split into two 40 u injections.
- Draw 1.6 mL bacteriostatic water; inject slowly.
- Swirl gently; avoid foaming.
- Label: “16 mg / 1.6 mL = 10 mg/mL (1 u = 100 µg)”.
Protocol Overview
Ara-290 targets the innate repair receptor to reduce inflammation and restore small-fiber nerve density.
- Goal: Mitigate neuropathic pain & enhance tissue repair
- Schedule: Daily Sub-Q or IM for 4 weeks, repeat after a 4 week break
- Dose Range: 2 – 4 mg daily (max 8 mg)
- Reconstitution: 2 mL (8 mg/mL) standard; 1.6 mL (10 mg/mL) advanced
- Storage: Lyophilized ≤ −20 °C; reconstituted 2 – 8 °C
Dosing Protocol
Daily injections sustain receptor activation for maximal nerve-repair signaling.
- Daily Dose: Start 2 mg; increase to 4 mg if tolerated
- Frequency: Inject once daily at consistent times
- Cycle Length: 28 days on → 28 days off
- Advanced: Up to 8 mg daily for refractory cases
- Route: Subcutaneous preferred; IM optional
Storage Instructions
Maintain cold-chain integrity to preserve peptide structure.
- Lyophilized: Store frozen (≤ −20 °C) up to 12 months
- Reconstituted: Refrigerate 2 – 8 °C; use within 28 days
- Keep away from light; avoid repeated freeze-thaw
- Discard if solution becomes cloudy or discoloured
Supplies Needed
Typical 4-week cycle uses one vial; stock extra for multiple cycles.
- Peptide Vials:
• 4 wks ≈ 1 vial
• 8 wks ≈ 2 vials - Insulin Syringes (1 mL, 100 u): 30 – 35 pcs per 4-week cycle
- Bacteriostatic Water: 1× 30 mL bottle
- Alcohol Swabs: 1 box
Important Notes
Practical tips to enhance safety and data integrity.
- Rotate injection sites to minimise irritation.
- Monitor fasting glucose & renal markers in long studies.
- Discontinue if hypersensitivity occurs; seek professional advice.
- For sub-10 unit doses, consider 50-unit syringes for precision.
How This Works
Ara-290 selectively activates the innate repair receptor (IRR), triggering anti-inflammatory and tissue-protective pathways without elevating red-cell mass.
- Neuroprotection: Promotes small-fiber nerve regeneration
- Anti-inflammatory: Down-regulates pro-inflammatory cytokines
- Metabolic Aid: Improves insulin sensitivity in diabetic models
Potential Benefits & Side Effects
Most users experience reduced neuropathic discomfort and enhanced recovery; adverse effects remain rare.
- Alleviates burning or tingling from small-fiber neuropathy
- Accelerates soft-tissue healing in preclinical studies
- Mild injection-site redness possible; headache uncommon
- No erythropoietic or hypertensive effects observed in trials
Lifestyle Factors
Support the peptide’s anti-inflammatory action with healthy habits.
- Adopt an anti-inflammatory, whole-food diet
- Engage in moderate exercise and active recovery
- Prioritise 7–9 hours of sleep nightly
- Manage stress through meditation or breathwork
Injection Technique
Simple guidelines for safe daily injections.
- Clean vial rubber stopper & injection site with alcohol swabs
- Insert needle at a 45–90° angle into subcutaneous tissue
- Inject slowly & rotate sites (abdomen, thigh, etc.)
Recommended Source
We recommend Pure Lab Peptides for high-purity Ara-290.
Why Pure Lab Peptides?
- Verifies ≥99% purity through independent lab testing
- Trusted by researchers seeking reliable results
- Follows rigorous manufacturing standards for consistent quality
Important Note
This guide is for educational purposes only. Always consult a qualified healthcare provider before starting or modifying any therapy.
References
-
PubMed
– Ara-290 diabetic neuropathy trial -
PubMed
– Cibinetide sarcoidosis SFN study -
PubMed
– Ara-290 dose-escalation safety -
ClinicalTrials.gov
– Cibinetide diabetic retinopathy -
BioSpace
– Orphan drug designation news