IGF-1 LR3 (1mg Vial) Dosage Protocol
Quickstart Highlights
IGF-1 LR3 1mg dosage protocol involves daily subcutaneous injections to support research related to muscle growth, recovery, and nutrient partitioning.
- Typically dosed from ~30mcg to 80mcg daily in a standard protocol
- Advanced protocols may range up to 100mcg daily
- Reconstitute to a practical concentration (up to 3mL) for accurate dosing
- Store lyophilized in the freezer; reconstituted in the refrigerator
- Frequent monitoring recommended; consult a qualified professional

Dosing & Reconstitution Guide
Educational guide for reconstitution and dosing protocol
Standard / Gradual Approach (3 mL = ~333 mcg/mL)
Week | Daily Dosage (mcg) | Units (per injection) |
---|---|---|
Weeks 1–2 | ~33 mcg once daily | 10 units |
Weeks 3–4 | 50 mcg once daily | 15 units |
Weeks 5–6 | 66 mcg once daily | 20 units |
Weeks 7–8 | 80 mcg once daily | 24 units |
Ideal for most research protocols in the 30–80mcg daily range. Reconstitute with 3 mL of bacteriostatic water to achieve ~333 mcg/mL concentration.
Note: If dosing below 10 units (e.g., 20mcg → 6 units), consider smaller syringes for precise measurement.
- Draw 3.0 mL of bacteriostatic water into a sterile syringe.
- Inject the water slowly along the vial wall to reduce foam.
- Gently swirl—avoid vigorous shaking.
- Store the reconstituted solution at 2–8 °C (refrigerator), protected from light.
Advanced / Aggressive Approach (2 mL = 500 mcg/mL)
Week | Daily Dosage (mcg) | Units (per injection) |
---|---|---|
Weeks 1–2 | 50 mcg once daily | 10 units |
Weeks 3–4 | 75 mcg once daily | 15 units |
Weeks 5–6 | 100 mcg once daily | 20 units |
Weeks 7–8 | 120 mcg once daily | 24 units |
Recommended for higher daily dosages (≥50mcg). Reconstitute with 2 mL of bacteriostatic water for a 500 mcg/mL solution.
Note: Protocols exceeding the total mg in a single vial will require additional vials.
- Draw 2.0 mL of bacteriostatic water into a sterile syringe.
- Slowly inject the water to minimize foam.
- Gently roll/swirl the vial—no vigorous shaking.
- Store the reconstituted solution at 2–8 °C (refrigerator), protected from light.
Protocol Overview
A concise summary of daily administration for 8–12 weeks.
- Goal: Support research on muscle growth, recovery, and performance
- Schedule: Daily subcutaneous injections for 8–12 weeks
- Dose Range: 30–80mcg daily (standard); up to ~100–120mcg (advanced)
- Reconstitution: Up to 3mL for easy measuring
- Storage: Keep lyophilized vials frozen; refrigerate after reconstitution
Dosing Protocol
Suggested once-daily injection approach, with options for gradual or advanced scaling.
- Daily Dose: Start as low as 30–33mcg; increase as tolerated
- Frequency: Once daily subcutaneous injection
- Cycle Length: Typically 8–12 weeks
- Maximum Dose: Advanced protocols may reach 120mcg daily
- Timing: Same time each day is recommended for consistency
Storage Instructions
Proper storage ensures peptide integrity.
- Lyophilized: Store in freezer (−20°C) until mixing
- Reconstituted: Refrigerate at 2–8°C
- Use within 30 days of reconstitution
- Avoid repeated freeze-thaw cycles
Supplies Needed
Ensure you have these on hand for an 8–16 week cycle.
- Peptide Vials:
• 8 wks ≈ 3–4 vials (depending on dosage)
• 12 wks ≈ 5–6 vials
• 16 wks ≈ 7–8 vials
(Higher daily mcg requires more vials) - Insulin Syringes:
• 1 syringe per day (8 wks ≈ 56 syringes, etc.) - Bacteriostatic Water: 1× 30ml
- Alcohol Swabs: 1 box
Important Notes
Practical tips to enhance safety and efficacy.
- Always use new, sterile insulin syringes & rotate injection sites.
- Monitor blood glucose levels if necessary to avoid hypoglycemia.
- Consult a professional if you observe any adverse reactions.
- Track progress throughout the protocol, adjusting dosage as needed.
How This Works
IGF-1 LR3 is a modified insulin-like growth factor 1 with an extended half-life for potential anabolic and recovery benefits.
- Extended Half-Life: Allows for once-daily administration
- Tissue Growth & Repair: May support muscle, bone, and connective tissue recovery
- Influences carbohydrate metabolism and protein synthesis pathways
Potential Benefits & Side Effects
Observed outcomes include enhanced recovery, but individual responses vary.
- Supports muscle tissue development and protein synthesis
- May assist in improved recovery time post-exercise
- Possible side effects include hypoglycemia, joint pain, or injection-site redness
- Rarely, excessive doses could lead to unwanted tissue growth
Lifestyle Factors
Complementary strategies for maximum benefit.
- Pair with a nutrient-dense, protein-focused diet
- Incorporate regular strength training and proper recovery methods
- Maintain consistent sleep and stress-management practices
Injection Technique
Simple guidelines for safe daily injections.
- Clean vial rubber stopper & injection site with alcohol swabs
- Insert needle at a 45–90° angle into subcutaneous tissue
- Inject slowly & rotate sites (abdomen, thigh, etc.)
Recommended Source
We recommend Pure Lab Peptides for high-purity IGF-1 LR3.
Why Pure Lab Peptides?
- Verifies ≥99% purity through independent lab testing
- Trusted by researchers seeking reliable results
- Follows rigorous manufacturing standards for consistent quality
Important Note
This guide is for educational purposes only. Always consult a qualified healthcare provider before starting or modifying any therapy.
References
-
Mayo Clinic
– Mecasermin overview for subcutaneous route -
PMC
– Research on IGF-1 functional roles -
USADA
– IGF-1 doping and WADA prohibition -
FDA
– Clinical data on IGF-1 for ALS -
Sigma-Aldrich
– Guidance on reconstitution procedures -
PMC
– Extended data on IGF-1 LR3 safety -
GenScript
– LR3 IGF-1 receptor-grade documentation -
PubMed
– Journal abstract on IGF-1 efficacy -
WebMD
– Insulin-like growth factor-1 discussion -
R&D Systems
– IGF-1 datasheet and lab protocols -
PubMed
– Another study on IGF-1 usage -
Novus Biologicals
– Recombinant IGF-1 product specification -
PMC
– Analysis on IGF-1 clinical outcomes