Sermorelin (10mg Vial) Dosage Protocol
Quickstart Highlights
Sermorelin 10mg dosage protocol often centers on daily subcutaneous injections aimed at promoting natural growth hormone release and supporting overall well-being.
- Common starting dose between 200 – 300 mcg per day
- Once-daily injections, typically before bedtime
- Gradual titration helps users assess tolerance and response
- Reconstitute with up to 3 mL for practical dosing measurements
- Store lyophilized in the freezer; keep reconstituted vials refrigerated

Dosing & Reconstitution Guide
Educational guide for reconstitution and daily dosing protocol
Standard / Gradual Approach (3 mL = ~3.33 mg/mL)
Weeks | Daily Dose (mcg) | Units (per injection) |
---|---|---|
Weeks 1–4 | 200 mcg | ~6 units |
Weeks 5–8 | 300 mcg | ~9 units |
Weeks 9–12 | 400 mcg | ~12 units |
Weeks 13–16 (Optional) | 500 mcg | ~15 units |
This approach suits most individuals starting with a moderate daily dose. Reconstitute with 3 mL to yield ~3.33 mg/mL (3333 mcg/mL). Note that 200 mcg (~6 units) is below 10 units. Using a smaller insulin syringe (e.g., 50 or 30-unit) may improve measurement accuracy.
- Draw 3.0 mL of bacteriostatic water into a sterile syringe.
- Inject the water slowly against the vial wall to minimize foaming.
- Gently swirl until dissolved (avoid shaking vigorously).
- Store the reconstituted solution at 2–8 °C (refrigerator), protected from light.
Advanced / Aggressive Approach (3 mL = ~3.33 mg/mL)
Weeks | Daily Dose (mcg) | Units (per injection) |
---|---|---|
Weeks 1–4 | 300 mcg | ~9 units |
Weeks 5–8 | 400 mcg | ~12 units |
Weeks 9–12 | 500 mcg | ~15 units |
Weeks 13–16 (Optional) | 600 mcg | ~18 units |
Recommended for those aiming for higher daily doses. Still reconstitute with 3 mL, creating ~3.33 mg/mL. Injections above 500 mcg/day should be assessed for tolerance and potential side effects.
- Draw 3.0 mL of bacteriostatic water into a sterile syringe.
- Slowly inject along the vial wall to minimize foam.
- Gently roll or swirl to dissolve the powder.
- Store the reconstituted solution at 2–8 °C (refrigerator), protected from light.
Protocol Overview
A concise summary of this daily injection regimen.
- Goal: Stimulate natural growth hormone (GH) release for support in recovery, metabolism, and overall wellness
- Schedule: Once-daily subcutaneous injections
- Dose Range: Typically 200–600 mcg per day, depending on goals
- Reconstitution: Up to 3 mL for user-friendly measurements
- Storage: Keep lyophilized vials frozen; refrigerate after reconstitution
Dosing Protocol
Suggested once-daily injection protocol for effective titration and minimized side effects.
- Daily Dose: Start around 200–300 mcg; increase gradually if desired
- Frequency: Inject once per day (often at bedtime to align with natural GH rhythms)
- Cycle Length: 8–16 weeks, with optional continuation based on goals
- Maximum Daily Dose: Up to ~600 mcg in advanced protocols
- Timing: Evening or pre-bedtime injection recommended for synergy with natural GH release
Storage Instructions
Proper storage ensures peptide stability and potency.
- Lyophilized: Freeze until mixing (−20°C)
- Reconstituted: Refrigerate at 2–8°C
- Avoid repeated freeze-thaw cycles
Supplies Needed
Ensure you have these on hand for an 8–16 week cycle.
- Peptide Vials:
• 8 wks ≈ 1 vial
• 12 wks ≈ 2 vials
• 16 wks ≈ 3 vials
(More if following higher daily doses) - Insulin Syringes:
• 8 wks ≈ 56 syringes (1 per day)
• 12 wks ≈ 84 syringes
• 16 wks ≈ 112 syringes - Bacteriostatic Water: 1× 30ml
- Alcohol Swabs: 1 box
Important Notes
Practical tips to enhance safety and efficacy.
- Always use sterile insulin syringes and rotate injection sites daily.
- Consistency is key; daily injections align with natural GH secretion patterns.
- Monitor for any adverse reactions; consult a professional if concerns arise.
- Track progress throughout the protocol and adjust dosage as guided.
How This Works
Sermorelin is a synthetic peptide that stimulates your pituitary gland’s release of natural growth hormone.
- GH Stimulation: Increases endogenous growth hormone production
- Physiological Regulation: Supports a more natural GH/IGF-1 feedback loop compared to exogenous GH
- May aid in recovery, energy, and lean tissue maintenance
Potential Benefits & Side Effects
Most users report improvements in recovery and general wellness, though individual experiences can vary.
- Enhances natural GH output and IGF-1 levels
- Potentially supports better sleep, tissue repair, and body composition
- Minor side effects: injection site redness, headache, or mild bloating
- Rare side effects: dizziness, numbness, or allergic reactions
Lifestyle Factors
Complement daily Sermorelin injections with these supportive habits.
- Maintain a nutrient-rich, balanced diet with adequate protein
- Incorporate regular physical activity and prioritize rest days
- Manage stress levels and ensure consistent sleep patterns
Injection Technique
Simple guidelines for safe daily injections.
- Clean vial rubber stopper & injection site with alcohol swabs
- Insert needle at a 45–90° angle into subcutaneous tissue
- Inject slowly & rotate sites (abdomen, thigh, etc.)
Recommended Source
We recommend Pure Lab Peptides for high-purity Sermorelin.
Why Pure Lab Peptides?
- Verifies ≥99% purity through independent lab testing
- Trusted by researchers seeking reliable results
- Follows rigorous manufacturing standards for consistent quality
Important Note
This guide is for educational purposes only. Always consult a qualified healthcare provider before starting or modifying any therapy.
References
-
Health Canada PDF
– Official drug product monograph for peptides -
PubMed Central
– GH release study in older adults -
Mayo Clinic
– Sermorelin injection route and description -
PubMed Central
– Investigating GHRH analogs for GH -
University of Maryland Archive
– Scholarly repository on Sermorelin data -
JCEM
– Journal of Clinical Endocrinology & Metabolism study