Cagrilintide 5mg + Semaglutide 5mg (10mg Blend) Dosage Protocol

Cagrilintide + Semaglutide (5/5mg Blend) Dosage Protocol

Quickstart Highlights

Cagrilintide 5mg + Semaglutide 5mg dosage protocol is designed to promote appetite regulation and metabolic benefits through once-weekly subcutaneous injections.

  • Typical starting dose of 0.25 mg of each compound (0.5 mg total) per week
  • Once-weekly injection schedule for simplicity
  • Gradual titration to improve tolerance and manage side effects
  • Reconstitute with 2ml for easy measuring
  • Store lyophilized in the freezer; reconstituted in the refrigerator
Cagrilintide 5mg + Semaglutide 5mg Vial

Protocol Overview

A concise summary of this once-weekly regimen.

  • Goal: Enhance weight management and metabolic regulation
  • Schedule: Weekly subcutaneous injections for 12–16 weeks (or longer)
  • Dose Range: Start at 0.25 mg of each compound (0.5 mg total) and gradually titrate up to 2 mg total or beyond, depending on goals
  • Reconstitution: Use 2ml of BAC water for accurate dosing
  • Storage: Keep lyophilized vials frozen; refrigerate after reconstitution

Dosing Protocol

Suggested once-weekly injection approach, balancing both peptides for optimal synergy.

  • Weekly Dose: Start with 0.25 mg of each peptide (0.5 mg total); increase as tolerated
  • Frequency: Inject once per week subcutaneously
  • Cycle Length: 12–16 weeks (extend as needed for ongoing research)
  • Maximum Dose: May escalate to 2 mg total or higher, depending on research objectives
  • Timing: Consistency of the day/time each week is recommended

Reconstitution

Guidelines for mixing the 10mg vial (5mg Cagrilintide + 5mg Semaglutide) with 2ml of bacteriostatic water.

  • Total Peptide Content: 10mg per vial (5mg + 5mg)
  • Concentration: 2ml yields a 5 mg/ml total solution
    • Each 0.1ml = 0.5 mg total (0.25 mg Cagrilintide + 0.25 mg Semaglutide)
    • An injection of 0.1ml delivers 0.5 mg total each week
  • Roll gently—do not shake
  • Use insulin syringes (29–31G) for accurate measurement

Storage Instructions

Proper storage preserves peptide integrity.

  • Lyophilized: Freeze until mixing (−20°C)
  • Reconstituted: Refrigerate at 2–8°C
  • Use within 30 days of reconstitution
  • Avoid repeated freeze-thaw cycles

Dosing Schedule

An example once-weekly protocol for up to 16 weeks, with optional escalation. (Each dose reflects the total of both peptides combined.)

Phase & Weeks Weekly Dose (Total) Approx. Units
Weeks 1–4 0.5 mg (0.25 mg each) 10 units
Weeks 5–8 1 mg (0.5 mg each) 20 units
Weeks 9–12 1.5 mg (0.75 mg each) 30 units
Weeks 13–16 (Optional) 2 mg (1 mg each) 40 units

Disclaimer: Some research protocols escalate to 3 mg or 4 mg total weekly. Doses above 2 mg should be approached cautiously and under professional guidance.

Supplies Needed

Have these items ready for a 12–16 week cycle.

  • Peptide Vials:
    • 12 wks ≈ 2 vials
    • 16 wks ≈ 2–3 vials (depending on dose escalation)
  • Insulin Syringes:
    • 12 wks ≈ 12
    • 16 wks ≈ 16
  • Bacteriostatic Water: 1× 30ml
  • Alcohol Swabs: 1 box
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Important Notes

Practical tips to enhance safety and protocol efficiency.

  • Always use new, sterile insulin syringes & rotate injection sites.
  • Maintain consistent weekly injections for optimal results.
  • Monitor for unwanted effects; consult a professional if concerns arise.
  • Track progress regularly, adjusting dosage per recommendations.

How This Works

This blend combines Cagrilintide (an amylin analog) with Semaglutide (a GLP-1 receptor agonist).

  • Hormone Pathways: Enhances satiety and regulates blood glucose
  • Metabolic Support: Assists in appetite control and weight management
  • Dual approach targets complementary pathways for improved outcomes

Potential Benefits & Side Effects

Many users report enhanced weight management and improved metabolic markers.

  • Encourages healthier glucose control
  • Supports body weight reduction goals
  • Possible mild side effects include nausea, dizziness, or GI discomfort
  • Rarely, injection-site irritation or headaches could occur

Lifestyle Factors

Additional considerations for maximizing benefits.

  • Opt for a balanced, nutrient-dense diet with sufficient protein
  • Include regular exercise and allow proper recovery
  • Manage stress levels and aim for adequate sleep each night

Injection Technique

Simple guidelines for safe daily injections.

  • Clean vial rubber stopper & injection site with alcohol swabs
  • Insert needle at a 45–90° angle into subcutaneous tissue
  • Inject slowly & rotate sites (abdomen, thigh, etc.)

Important Note

This guide is for educational purposes only. Always consult a qualified healthcare provider before starting or modifying any therapy.

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